Using three-point bending to evaluate tibia bone strength in ovariectomized young mice
نویسندگان
چکیده
منابع مشابه
Tibia bone properties at different time course of ovariectomized rats
BACKGROUND The model of bilaterally ovariectomized rats mimics the accelerated bone loss observed in postmenopausal women due to estrogen deficiency. Although calcium is main mineral in bone, previous study in human showed there is hypermineralization and higher calcium level in hydroxyapatite crystal structure from osteoporosis patients. This study was aimed to investigate the effect of time c...
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BACKGROUND The objective of this study was to determine the influence of loading frequency on the failure of articular cartilage-on-bone specimens under three-point bending. METHODS In this study, cyclic three-point bending was used to introduce failure into cartilage-on-bone specimens at varying loading frequencies. Sinusiodally varying maximum compressive loads in the range 40-130 N were ap...
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Estrogens play a key role in an extensive range of physiological functions in various types of tissues throughout the body in females. We previously showed that estrogen insufficiency caused muscle weakness that could be rescued by estrogen administration in a young female ovariectomized (OVX) mouse model. However, long-term estrogen replacement therapy increases risks of breast cancer and card...
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using computation software to simulate fracture behaviors of structures can shorten the time to estimate safety of engineering structures and reduce a lot of cost of experiment. However three dimensional numerical simulation for fracture process is a challenging issue, because the convergence and accuracy are not easily obtained and high computational cost is generated. In this paper, three new...
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ژورنال
عنوان ژورنال: Journal of Biological Physics
سال: 2017
ISSN: 0092-0606,1573-0689
DOI: 10.1007/s10867-016-9439-y